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TOPIC: Celiac disease in Women w/ Endometriosis

Celiac disease in Women w/ Endometriosis 07 Oct 2010 10:52 #4267

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Pub Med link

Clin Exp Obstet Gynecol. 2009;36(1):23-5.

Serological testing for celiac disease in women with endometriosis. A pilot study.
Aguiar FM , Melo SB , Galvão LC , Rosa-e-Silva JC , dos Reis RM , Ferriani RA .

Sector of Human Reproduction, Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, SP, Brazil.

Abstract
PURPOSE OF INVESTIGATION: Celiac disease (CD) involves immunologically mediated intestinal damage with consequent micronutrient malabsorption and varied clinical manifestations, and there is a controversial association with infertility. The objective of the present study was to determine the presence of CD in a population of infertile women with endometriosis.

METHODS: A total of 120 women with a diagnosis of endometriosis confirmed by laparoscopy (study group) and 1,500 healthy female donors aged 18 to 45 years were tested for CD by the determination of IgA-transglutaminase antibody against human tissue transglutaminase (t-TGA) and anti-endomysium (anti-EMA) antibodies.

RESULTS: Nine of the 120 women in the study group were anti-tTGA positive and five of them were also anti-EMA positive. Four of these five patients were submitted to intestinal biopsy which revealed CD in three cases (2.5% prevalence). The overall CD prevalence among the population control group was 1:136 women (0.66%).

CONCLUSION: This is the first study reporting the prevalence of CD among women with endometriosis, showing that CD is common in this population group (2.5%) and may be clinically relevant.

PMID: 19400413 [PubMed - indexed for MEDLINE]

Celiac disease in Women w/ Endometriosis 07 Oct 2010 10:57 #4268

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Non-Celiac Gluten sensitivity would however test higher in this group if there was a widely available serum blood test available. If you have endometriosis you may consider a trial gluten free diet or stool test through http://www.enterolab.com

Lactose intolerant and casein (dairy protein) sensitivity may also be a problem in this population.

Celiac disease in Women w/ Endometriosis 27 Dec 2010 21:08 #4269

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Don't know why we aren't doing this in the US!
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