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What is Gluten and Dairy Intolerance? What is the difference between an allergy and intolerance/sensitivity. Latest medical research. Open to the public.
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TOPIC: Food Allergens and Respiratory problems

Food Allergens and Respiratory problems 02 Nov 2009 13:53 #617

  • Debra
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Have you noticed increased respiratory problems after eating dairy, wheat or eggs? Coughing, harder time breathing? It could be a food sensitivity or delayed food allergy. Food allergens manifest differently in people. I will post several studies regarding the connection between food allergies/sensitivities and  respiratory problems here on this thread

Pediatr Gastroenterol Nutr. 2008 Nov;47 Suppl 2:S45-8.

Food allergy as seen by an allergist.
Cox HE .

Consultant in Paediatric Allergy, Imperial College, London, UK.

The clinical expression of allergic disease is the consequence of a series of complex gene-environment interactions that occur at the materno-fetal interface and throughout infancy, leading to persistence of the Th2 immune response. It has been proposed that atopic eczema is the cutaneous manifestation of a systemic disorder that also gives rise to asthma, food allergy, and allergic rhinitis. The recent emergence of genes regulating epidermal barrier function has raised the question of whether the skin barrier in atopic eczema is defective from the outset, rendering the epidermis "leaky," thereby increasing the risk of allergen penetration and the succeeding inflammatory reaction that contributes to atopic eczema. Food allergic sensitisation and eczema frequently coexist during the first 2 years of life, and food allergy is more prevalent in infants and children with moderate to severe eczematous inflammation. The majority of food allergic reactions are caused by 8 foods, with milk, egg, and peanut occurring with greatest frequency. The acquisition of food-specific tolerance occurs predominantly with foods in which the epitopes are grouped together in a conformational structure (milk, egg, wheat, soy), whilst it rarely occurs in patients allergic to foods in which the epitopes are arranged in a linear fashion (nuts, seeds, fish). Better tests and novel therapies, such as immunotherapy and oral tolerance induction, are required for the management of food allergy.

PMID: 18931600 [PubMed - indexed for MEDLINE]


Food allergens and respiratory symptoms .
Jesenak M , Rennerova Z , Babusikova E , Havlicekova Z , Jakusova L , Villa MP , Ronchetti R , Banovcin P .

Department of Pediatrics, Comenius University in Bratislava, Jessenius School of Medicine, Martin, Slovakia. This email address is being protected from spambots. You need JavaScript enabled to view it.

Food allergy may be clinically expressed by a variety of respiratory symptoms, which can be provoked either by IgE- or cellular mediated reactions. Among the diagnostic procedures, newly introduced atopy patch test seems to be important for diagnosis of cellular, delayed immune reactions.

We studied the prevalence of positive atopy patch tests with food and inhalant allergens and the correlation between the positivity of atopy patch tests and questionnaire derived atopic and nonatopic espiratory symptoms and diseases in an unselected children population.

 We found a correlation between the positive patch test result with wheat and cough after physical effort, allergic rhino-conjunctivitis, and bronchitis recidivans. The subjects with positive skin reaction to egg suffered from allergic rhino-conjunctivitis and bronchial asthma. Food and inhalant allergens play an important role in the induction and exacerbation of some respiratory allergic diseases. The positive correlation of positive results of skin tests and history of some respiratory diseases and symptoms also on the population level confirm the importance of these tests in the diagnostic work-up of these allergic diseases.

PMID: 19218655 [PubMed - indexed for MEDLINE]

J Asthma.2008 Dec;45(10):862-6.

Food allergy is associated with potentially fatal childhood asthma.
Vogel NM , Katz HT , Lopez R , Lang DM .

The Children's Hospital, The Cleveland Clinic Foundation, Center for Pediatric Allergy and Immunology, Cleveland, Ohio 44195, USA. This email address is being protected from spambots. You need JavaScript enabled to view it.

BACKGROUND: Risk factors for potentially fatal childhood asthma are incompletely understood. OBJECTIVE: To determine whether self-reported food allergy is significantly associated with potentially fatal childhood asthma. STUDY DESIGN: Medical records from 72 patients admitted to a pediatric intensive care unit (PICU) for asthmatic exacerbation were reviewed and compared in a case-control design with 2 randomly selected groups of 108 patients admitted to a regular nursing floor for asthma and 108 ambulatory patients with asthma. Factors evaluated included self-reported food allergy, gender, age, poverty area residence, race/ethnicity, inhaled steroid exposure, tobacco exposure, length of hospital stay, psychologic comorbidity, and season of admission.

RESULTS: At least one food allergy was documented for 13% (38/288) of the patients. Egg, peanut, fish/shellfish, milk, and tree nut accounted for 78.6% of all food allergies. Children admitted to the PICU were significantly more likely to report food allergy (p = 0.004) and 3.3 times more likely to report at least one food allergy compared with children admitted to a regular nursing floor, and significantly more likely to report food allergy (p < 0.001) and 7.4 times more likely to report at least one food allergy compared with children seen in the ambulatory setting. Children admitted to either the PICU or the regular nursing floor were significantly more likely be African-American (p < 0.001) and to be younger (p < 0.01) compared with children seen in the ambulatory setting. CONCLUSIONS: Self-reported food allergy is an independent risk factor for potentially fatal childhood asthma. Asthmatic children or adolescents with food allergy are a target population for more aggressive asthma management.

PMID: 19085574 [PubMed - indexed for MEDLINE]

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