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What is Gluten and Dairy Intolerance? What is the difference between an allergy and intolerance/sensitivity. Latest medical research. Open to the public.
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TOPIC: U of M Celiac Center Update on Research

U of M Celiac Center Update on Research 18 Dec 2010 14:55 #632

  • Debra
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Once someone donates to the Celiac Center at the University of Maryland you get placed on their e-mail updates, I guess that's a good thing in this case since they put a very nice update together. FYI, they are also doing research on non-celiac gluten sensitivity.

[align=center]Dr. Fasano and the CFCR:
Increasing CD Awareness by TenFold!
HIGHLIGHTS OF OUR RESEARCH  [/align]
  • Natural History of Celiac Disease Autoimmunity in a USA Cohort followed since 1974 - This study was published in September in the Annals of Medicine and shows that since 1974, the incidence of CD in the U.S. has doubled every 15 years.
  • Intestinal Stem Cell Initiative - We are leading a new international initiative, funded in part by the Vatican, to explore the therapeutic potential of adult intestinal stem cells.
  • Institute for Autoimmunity & Inflammation - Recently we received a pledge to establish a research institute focused totally on autoimmunity and inflammation.  We are very fortunate that the Center for Celiac Research will be an integral part of this institute.  Therefore, we are confident that with your continued support, our quest to increase the quality of life for our celiac disease and gluten sensitive patients and their families will progress even faster.
  • Innate Immune Study - The CFCR is currently investigating the body's natural response to gliadin in people with and without CD to identify the very early event(s) which are responsible for the development of gluten spectrum disorders, including CD and gluten sensitivity.  Understanding these pathways may offer new preventive and therapeutic strategies for CD and possibly other autoimmune diseases.
  • Infant Nutrition and Risk of Celiac Disease: Proposal for an Intervention, Prospective, Multicenter Study - The CFCR continues to work on this study and has enrolled over 600 babies worldwide to establish the possibility of a timeframe in which the introduction of gluten to an infant's diet may prevent the onset of CD in genetically at-risk infants.  The Center will follow these children, until 18 years of age, to determine if the timing of gluten introduction affects the development of CD or merely delays the onset.  We are on the verge of expanding to 40 centers worldwide with over 1,000 babies enrolled in the U.S. alone.  To enroll in this study, please visit our website and click on research.
  • Possible Link Between Schizophrenia and CD/Gluten-Sensitivity - There is evidence of a link between schizophrenia and CD that dates back as far as 1961. A theory for this association suggests that gluten serves as an environmental trigger in individuals predisposed to schizophrenia. This theory is supported by a series of ecologic data linking a decreased prevalence of schizophrenia with low grain consumption. The CFCR is currently investigating this link with 1,419 schizophrenic patients and the preliminary observations suggest that 1 out of 5 could be affected by gluten sensitivity and, therefore, can potentially benefit from a gluten-free diet. This pilot study was published in June 2009 in the Schizophrenia Bulletin.
  • Navajo Population & CD - This study will help determine if the current prevalence of CD among the Navajo population is severely under diagnosed.
  • Celiac Disease Research Registry - The CFCR's celiac disease registry continues to expand, which will enable us to learn more about gluten related disorders, their complications and co-morbidities.
  • CFCR Master's Class in Celiac Disease - We are very proud to report that the third class of students will graduate in December 2010.  Given the high demand, our Master's Program in CD will go online to allow more students worldwide to attend our classes.
  • Summer Internships - This past summer we had 18 students from several countries including Italy, France, and the U.S.  Students participating in the program ranged from high school, graduate, medical school, and PhD students.  Depending on the individual student's strengths and interest, the students were paired with staff and were able to participate in most areas of research currently active at the CFCR.
  • Celiac Disease Diagnosis: Simple Rules Are Better Than Complicated Algorithms - New guidelines were published in the American Journal of Medicine recommending that a subgroup of individuals can be diagnosed with CD without the necessity to perform an endoscopy with intestinal biopsy, thus achieving one of our previous goals.
  • Update on Alba Therapeutics - The CFCR continues to focus some of its research activities to develop alternative/integrated strategies to the gluten-free diet.  Our efforts continue to provide the rationale for Alba Therapeutics to perform the clinical trials necessary to exploit these strategies.

U of M Celiac Center Update on Research 18 Dec 2010 15:03 #633

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More from the newsletter:

OUR GOALS FOR THE FUTURE
  • To better understand the genetics of CD
  • To continue developing innovative strategies for the treatment and prevention of CD
  • To continue to provide the most accurate and up-to-date information on CD to health care professionals, government agencies and industry
  • To study the psychological impact on the newly diagnosed patients and their families
  • In conjunction with John Hopkins University there is currently a proposal for a randomized double blind, controlled trial to determine the effectiveness of the gluten-free diet in the treatment of schizophrenia
  • In conjunction with the Navajo Nation we will be embarking on a study to determine the prevalence of celiac disease in the Navajo population
  • [align=left]To kick off the largest prospective study on infants at risk for CD to establish the natural history of the disease and identify preventive and therapeutic interventions
HOW YOU CAN GET INVOLVED

Gluten-Free North Sea Getaway Cruise/Tour - Joins Bob & Ruth's Gluten-Free Dining & Travel Club, Dr. Fasano and his wife, Jo Ann, on this wonderful excursion to the North Sea.  A portion of the trip cost will be a tax deductible donation to the CFCR.  See http://www.bobandruths.com for more information.

10th International Walk/Run for Celiac Disease - Time to celebrate 10 years of Making Tracks for Celiacs!  Cities continue to join our efforts to increase the awareness of CD and to raise funds for local and national initiatives and research.  Over the past 9 years, over $2 million has been raised.  Visit http://www.celiacwalk.org for more information on how to join our efforts.

Donate to the CFCR through Op4G - Participate in online market research and donate the earnings to the CFCR.  Visit our website for more information.

Chip in for Celiac - The 2nd annual CT golf tournament was a success!  See our website for more information and organize one in your area.

NEW TriBandz Celiac Awareness Bracelets - We are proud to announce our new celiac awareness bracelets for sale now on our website.  These new bracelets (3 different sizes) have a variety of inserts that you can pop in & out, and/or trade with friends.  These bracelets help raise awareness and funds for celiac research.

Controllable Christmas Lights for Celiac - Celebrate the holidays, increase CD awareness and raise funds for the CFCR http://www.komar.org .  More than $55,000 has been raised through this enjoyable site.  Email your friends! 
 
Estate Planning - Have you remembered the CFCR in your estate planning?  http://www.celiaccenter.org/plannedgiving . [/align][/list]

U of M Celiac Center Update on Research 04 Feb 2011 17:54 #634

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